This peer-reviewed publication in Biomedicines provides a comprehensive scientific framework linking metabolic dysfunction, insulin resistance, and neurodegeneration during aging. The study highlights D-Pinitol as a multifunctional inositol capable of modulating key endocrine and metabolic pathways involved in age-related disorders, including impaired insulin signaling, oxidative stress, inflammation, and tau pathology.
The findings position D-Pinitol as a nutraceutical tool that acts upstream of disease progression, supporting metabolic homeostasis with downstream benefits for pancreatic function, liver metabolism, and brain health. This work establishes the scientific foundation of Agelity® as a metabolic-endocrine modulator relevant to healthy aging and cognitive decline.