Gyneos

Overview

Designed for
Women at every life stage—from adolescence through postmenopause. Ideal for those managing PCOS, hormonal imbalances, mild metabolic concerns, or seeking support for cognitive and bone health during menopause and beyond.

Why It Works
Clinically backed, naturally sourced, and well-tolerated. Gyneos® helps balance hormones, improve insulin sensitivity, and support brain and bone function—leveraging 30+ years of scientific expertise.

How to Use
Take daily. Many users report feeling benefits—like better balance and energy—within just a few weeks. Continued use over 2–3 months maximizes long-term results.

Formulation targets
Perfect for women’s health products targeting hormonal balance, fertility support, bone strength, and healthy aging.

Discover how Gyneos® can empower women’s health naturally.

Disclaimer:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Appearance:

White to off-white-crystalline powder.

Melting range:

ca. 230ºC

Taste:

Only slightly sweet, no distinct side-or aftertaste.

Assay (USP):

min. 98 %.

Loss on drying:

máx. 2%.

Solubility:

Highly soluble in water.

Stability:

Stable under normal processing and storage conditions.

Science-backed metabolic and hormonal regulation supporting women’s health from adolescence and fertility to menopause and cognitive aging

Gyneos® is derived from Ceratonia siliqua, the carob tree native to the Mediterranean basin. Traditionally used for its rich nutritional value, carob pods contain high levels of D-Chiro-inositol (DCI) — a naturally occurring molecule shown to support female reproductive health, metabolic function, and hormonal balance.

Gyneos® delivers >98% pure D-Chiro-inositol from carob. Fully traceable, solvent-free and ideal for PCOS, bone health, metabolic balance and healthy aging

Ultra-Pure DCI

98% purity from carob with pharma-grade precision

Fully Water-Soluble

Dissolves easily in any format — no binders, no grit

Triple Action Support

Restores ovulation, reduces insulin resistance, balances hormones

One Simple Dose

Daily support for ovulation deficits, bone restoration and metabolic balance

100% natural and traceable
Produced entirely in Spain from carob, full supply chain control

The richest natural source of D-Chiro-inositol.

A powerful compound from a resilient tree.

While myo-inositol is very presence in foods and many plants, DCI is essential as key player for metabolic issues and carob pods offers one of the most concentrated and sustainable sources. At Advenion, we extract DCI through proprietary solvent-free technologies, developed over 20+ years of biotech experience. This process yields a high-purity (>98%) natural inositol, free from synthetic residues and fully traceable to its Mediterranean origin.

Clinically studied. Naturally effective.

Preclinical and clinical research has demonstrated within last 30 years that DCI improves ovulatory function, reduces insulin resistance, and restores hormonal balance in women with PCOS or age-related infertility. With Gyneos®, Advenion delivers this proven compound in a pharmaceutical-grade format, offering science-backed results with nature’s integrity.

Mechanism of action

1. Insulin Signaling and Sensitization

2. Regulation of Ovarian Steroidogenesis

3. Enhancement of Glycogen Synthesis

4. Improvement of Lipid Metabolism

5. Anti-Inflammatory and Antioxidant Effects

6. Modulation of CDK5, a key switch in brain health

HEALTHY REPRODUCTION

HEALTHY METABOLISM

HEALTHY AGING

Features & Benefits

Clinically Driven Benefits

• Boosts natural ovulation

• Supports healthy insulin response

• Promotes bone strength and density

• 100% hormone-free and well-tolerated

• Multi-targeted action across systems

• Helps with focus, clarity, and emotional balance.

Formulation Advantages

• Fully water-soluble and easy to blend

• Neutral taste, ideal for any format

• Heat-stable for manufacturing flexibility

• ≥98% pure DCI – pharma-grade

• Adjustable dosing based on need

• Validated with over 30 years of expertise

Ingredients Excellence

Vegetarian

Vegan

Pesticide free

Non GMO

No solvents

No added sugars

Made in EU

Low GI

Gluten free

Proven Health Impact

Source directly from farmers

Skin Tanning Effect

Satiating Effect

Reduced PCOS

Patent

Mood Support

Mental Illness Help

Liver Health

Increses Fertility

Improves Vision

Blood Glucose Control

Trusted Certifications

Kosher

ISO 9001

ISO 22000

ISO 14001

Halal

GMP

FDA

Propietary Research

Science-backed Evidence for Women’s Health

Gyneos® improve fertility: Intake of Gyneos (DCI) improves ovary function, embryo development and implantation. From: Pericuesta E, et al. . D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome. Int J Mol Sci. 2020 Aug 22;21(17):6049

Gyneos® administered to aged mice improves fertility

Gyneos® restore fertility in preclinical models of PCOS ore fertility in preclinical models of PCOS

Gyneos® improves insuling signaling, helping to fight insulin resistance and its associated disorders

CLINICAL RESEARCH HIGHLIGHTS:

1. Improves Insulin Sensitivity

DCI supplementation enhances insulin signaling, lowering fasting insulin and improving glucose tolerance in women with PCOS and in patients with insulin resistance or type 2 diabetes.

2. Reduces Hyperandrogenism in PCOS

Clinical trials show DCI reduces circulating testosterone and other androgens, helping to alleviate symptoms like acne, hirsutism, and menstrual irregularities.

3. Restores Ovulation and Fertility

By normalizing insulin response and reducing hyperandrogenism, DCI supports follicular development and ovulation, improving spontaneous pregnancy rates in women with PCOS.

4. Benefits Metabolic Health Beyond PCOS

Evidence points to improved lipid profiles, reduced triglycerides, and lower blood pressure in some cohorts, highlighting potential benefits in metabolic syndrome management .

D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome Pericuesta E, Laguna-Barraza R, Ramos-Ibeas P, Gutierrez-Arroyo JL, Navarro JA, Vera K, Sanjuan C, Baixeras E, de Fonseca FR, Gutierrez-Adan A. Int J Mol Sci. 2020 Aug 22;21(17):6049

Read the full article

Early Oral Administration of D-Chiro-Inositol Reverses Hippocampal Insulin and Glutamate Signaling Deficits in the 3×Tg Humanized Mouse Model of Alzheimer’s Disease Pacheco-Sánchez B et al_2025_Nutrients.

Read the full article

Dietary administration of D-chiro-inositol attenuates sex-specific metabolicimbalances in the 5xFAD mouse model of Alzheimer’s disease Lopez-Gambero AJ et al_2022_Biomedicine & Pharmacotherapy

Read the full article

The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases Lopez-Gambero AJ et al_2020_Biomedicines

Read the full article

Market Opportunities

Women’s health

Supporting vitality, hormonal health, and performance across every life stage. From early adulthood to healthy aging.

Weight and metabolic management

Evidence-driven metabolic and appetite homeostasis

Cognitive performance

Supporting mental clarity, focus, and long-term memory brain function.

Joint & bone

Supporting structural integrity and mineral balance of bones.

Applications

Tablets

Sticks Packs

Soft Gels

RTDS / Shots

Powders

Gummies

tableta-amarilla-efervescente-que-se-disuelve-en-un-vaso-transparente-de-agua-ia-generativa

Effervescents

Confectionery

Chews

Capsules

disposicion-de-bebidas-saludables-de-vista-superior

Beverages

saludables-deliciosas-barras-de-granola-con-chocolate-barras-de-muesli-con-nueces-y-frutas-secas-vista-superior

Bars

Bakery

Origins

Rooted in the Mediterranean, crafted with purpose.

Gyneos® begins its story in the rugged landscapes of the Mediterranean basin, where the resilient carob tree (Ceratonia siliqua) has flourished for centuries. Its pods are a natural source of D-Chiro-inositol, clinically linked to fertility and metabolic health. At Advenion, we combine this ancient crop with modern precision to deliver a clean, plant-based solution for women’s health.

Born from science, focused on women.

Gyneos® is produced in Malaga, Spain—the birthplace of Euronutra, Advenion’s parent company and a pioneer in natural D-Chiro-inositol extraction. More than 30 years ago, we introduced the first solvent-free technologies to isolate this molecule at scale, achieving >98% purity. This breakthrough not only set a new industry standard in quality and sustainability but also laid the foundation for innovative solutions dedicated to women’s health.

Made in Europe, trusted worldwide.

Our vertically integrated process starts with EU-sourced carob pods and continues under our control through every step: extraction, purification, standardization, and in-house quality testing. This short and transparent supply chain ensures consistency, safety, and pharmaceutical-grade standards batch after batch.

Total traceability, from tree to treatment.

At Advenion, we’re not just close to our raw materials . We’re embedded in the entire process. Full ownership of production means we can guarantee traceability and integrity at every stage. Rigorous testing in our certified labs confirms that each batch of Gyneos® delivers stable, effective, and clean D-Chiro-inositol. Just as nature intended.

Empowering natural fertility.

Gyneos® was designed to help women regain balance, naturally. It targets key drivers of ovulation and insulin resistance, making it a gentle but effective option for those with PCOS or age-related fertility challenges. No hormones. No invasive treatments. Just one simple, science-backed ingredient that supports women — body and mind.

Disclaimer:
The information presented in this page is intended to provide general information on our premium products, their properties and potential applications. It is based on our present state of knowledge and must not be construed as guaranteeing specific properties or approvals of the products described herein or their suitability for any application described. The user is solely responsible for compliance with the existing approvals in the county of use. It is also the sole responsibility of the user to investigate whether existing patents are infringed by the use of the materials described herein. Adequate quality of our products is guaranteed under our General Conditions of Sales. All statements in this page have not been evaluated by the US Food and Drug Administration or EFSA. This product is not intended to diagnose, treat, cure, or prevent any disease.

D-Chiro-Inositol for Women’s Metabolic & Hormonal Health Across Life Stages

Overview

Appearance:

Melting range:

Taste:

Assay (USP):

Loss on drying:

Solubility:

Stability:

Science-backed metabolic and hormonal regulation supporting women’s health from adolescence and fertility to menopause and cognitive aging

100% natural and traceable Produced entirely in Spain from carob, full supply chain control

Mechanism of action

HEALTHY REPRODUCTION

HEALTHY METABOLISM

HEALTHY AGING

Features & Benefits

Clinically Driven Benefits

Formulation Advantages

Ingredients Excellence

Proven Health Impact

Trusted Certifications

Propietary Research

Science-backed Evidence for Women’s Health

Gyneos® administered to aged mice improves fertility

Gyneos® restore fertility in preclinical models of PCOS ore fertility in preclinical models of PCOS

Gyneos® improves insuling signaling, helping to fight insulin resistance and its associated disorders

CLINICAL RESEARCH HIGHLIGHTS:

1. Improves Insulin Sensitivity

2. Reduces Hyperandrogenism in PCOS

3. Restores Ovulation and Fertility

4. Benefits Metabolic Health Beyond PCOS

Market Opportunities

Applications

Origins

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100% natural and traceable
Produced entirely in Spain from carob, full supply chain control