This peer-reviewed publication in Biomedicines provides a comprehensive scientific framework linking metabolic dysfunction, insulin resistance, and hormonal imbalance to key aspects of women’s health across life stages. The article highlights the role of D-chiro-inositol (DCI) as a central regulator of insulin signaling, ovarian function, and systemic metabolic balance.
The review connects DCI deficiency and impaired inositol metabolism with conditions such as polycystic ovary syndrome (PCOS), fertility decline, metabolic dysfunction during menopause, and increased vulnerability to age-related cognitive impairment. By addressing insulin sensitivity and hormonal regulation through the PI3K/Akt pathway, DCI emerges as a foundational nutraceutical for supporting female reproductive health, metabolic resilience, and healthy aging.
This work establishes the scientific rationale for Gyneos® as a women-specific metabolic and hormonal modulator rather than a symptom-targeted ingredient.